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February 05, 2021
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Surface Ophthalmics begins phase 2 SURF-200 dry eye trial

The first patient has been dosed in a phase 2 clinical trial for SURF-200 investigating treatment for acute dry eye, according to a press release from Surface Ophthalmics.

Two low-concentration formulations of betamethasone in Klarity vehicle are under study in the dose-ranging trial that will enroll between 120 and 140 patients. Primary endpoint is symptom improvement measured at day 8, according to the release.

“With a proven diluent designed to protect the ocular surface and a potent corticosteroid, I’m hopeful that SURF-200 will provide a much-needed treatment option,” Preeya Gupta, MD, lead investigator for the trial, said in the release.

Surface Ophthalmics also has a phase 2 trial investigating SURF-100 (mycophenolate sodium and betamethasone sodium phosphate in Klarity vehicle) for chronic dry eye treatment.