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ARMOR study reports trends in antibiotic resistance over 10 years
VANCOUVER, British Columbia — The 10-year results of the ARMOR study confirmed the previously reported decrease in methicillin resistance among Staphylococcus aureus but not coagulase-negative staphylococci, according to a Bausch + Lomb press release.
The ongoing Antibiotic Resistance Monitoring in Ocular Microorganisms surveillance study (ARMOR) tracks in vitro antibiotic susceptibility profiles among ocular bacterial pathogens. Researchers reported resistance trends for 2,108 S. aureus and 1,721 coagulase-negative staphylococci (CoNS) collected since January 2009.
This analysis confirmed previous reports of a decrease in methicillin resistance among S. aureus (P < .001), with a 40% reduction in 2018. However, this decrease was not seen in CoNS, with about half of CoNS exhibiting methicillin resistance each year, according to the release.
Decreased resistance was also observed in S. aureus to azithromycin, ciprofloxacin, tobramycin and chloramphenicol.
In 2018, 414 isolates were collected from 15 participating sites. Staphylococci resistance rates remained similar to 2017 rates, with resistance to azithromycin, oxacillin/methicillin and ciprofloxacin. CoNS isolates revealed a resistance to trimethoprim and tobramycin. Multidrug resistance was observed in 30% of S. aureus and 40% of CoNS, with a prevalence ranging from 72% to 77% for methicillin-resistant staphylococci.