February 05, 2019
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Okogen begins phase 2 trial of adenoviral conjunctivitis treatment
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Okogen has initiated a phase 2 clinical trial to evaluate the safety and efficacy of OKG-0301 for the treatment of acute adenoviral conjunctivitis.
OKG-0301 is a topical ophthalmic formulation of ranpirnase, which is a targeted ribonuclease with broad-spectrum antiviral properties that is found naturally in tears, according to a company press release.
The multicenter, randomized, placebo-controlled, double-masked RUBY trial will evaluate multiple doses of OKG-0301 in 219 adult patients with acute adenoviral conjunctivitis. Researchers will assess the treatment’s ability to reduce viral burden, safety and potential to diminish longer-term complications of adenoviral infection.
Adenoviral conjunctivitis does not have any approved treatments.