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No cases of bilateral endophthalmitis reported after same-day injections
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PONTE VEDRA, Fla. — No cases of bilateral endophthalmitis were reported in a large study of patients who received bilateral same-day intravitreal anti-VEGF injections, according to a poster presented at the Women in Ophthalmology 2018 Summer Symposium.
“Prior to this study, the largest study looking at bilateral same - day injections was about 2,000 injections and was not really powered to look at endophthalmitis since it’s so rare,” presenting author Durga S. Borkar, MD, told Healio.com/OSN.
Of 101,932 bilateral same-day intravitreal injections in 5,890 patients, Borkar and colleagues from Wills Eye Hospital found the overall rate of endophthalmitis was 0.027%, comparable to findings of studies looking at unilateral injections in which infection rates ranged from 0.008% to 0.092%.
In this study, which derived data from the medical and billing records of the hospital’s multi-site retina service over more than 4 years, 28 cases of unilateral endophthalmitis were identified by ICD-9 or ICD-10 diagnosis codes. T here were no significant differences in infection rates based on which anti-VEGF was used.
“Of the 28 patients that had a unilateral case of endophthalmitis, almost 60% of them resumed bilateral same - day injections after they had recovered, which is consistent with prior surveys that have been done,” Borkar said. “ They really strongly prefer bilateral same - day injections when they have bilateral pathology.” – by Patricia Nale, ELS
Reference:
Borkar DS, et al. Endophthalmitis rates after bilateral same day intravitreal anti-VEGF injections. Presented at: Women in Ophthalmology 2018 Summer Symposium; Aug. 16-19, 2018; Ponte Vedra, Fla.
Disclosure: Borkar reports no relevant financial disclosures.