August 31, 2018
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BCVA improves in second decade despite muscle surgery in children with albinism

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Extraocular muscle surgery done in children with albinism in the second decade of life did not affect improvement in best corrected visual acuity, which typically improves in these patients during that period regardless of surgery.

A retrospective, longitudinal study of 41 patients with albinism who underwent one clinic visit between the ages of 10 and 13 and a second between the ages of 17 and 20 evaluated the effect of albinism type and extraocular muscle surgery on best corrected visual acuity.

The BCVA ranged from 20/25 to 20/160 during the first visit and from 20/20 to 20/125 on the second visit. Forty of the patients (98%) demonstrated a statistically significant improvement in BCVA from visit 1 to visit 2. Mean BCVA at visit 1 of 20/65 improved to 20/51 at visit 2 (P < .001).

Additionally, 14 patients underwent extraocular muscle surgery between visit 1 and visit 2. BCVA improved in nine patients and remained stable in five, but the surgery did not have a statistically significant effect on BCVA improvement when compared with improvement in those who did not undergo the surgery.

Disclosures: The researchers report no relevant financial disclosures.