June 28, 2018
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Patients may tolerate plain gut sutures better than polyglactin 910 sutures

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Data from a prospective study showed patients experienced improved tolerability and reduced inflammation if they received plain gut suture after undergoing 23-gauge pars plana vitrectomy compared with 8-0 polyglactin 910 suture.

The study included 49 eyes of 49 patients who underwent 23-gauge pars plana vitrectomy. The eyes were randomized to sclerotomy closure with either plain gut suture, Vicryl (polyglactin 910) or a combination of both sutures.

“With small-incision vitrectomy surgery, sutures have become less common but are still necessary on occasion. Many of the patients are bothered more postoperatively by the sutures than they are by the actual procedure. We found in our randomized trial that when we have to use sutures, the patients have more comfort and less inflammation using plain gut suture compared to Vicryl suture. Vicryl had been our standard suture for many years, but based on based our research, we have switched over to using plain gut whenever possible,” Sunir J. Garg, MD, FACS, co-author of the study, told Healio.com/OSN.

At 1 month after surgery, greater pain was reported in the polyglactin 910 group compared with the plain gut group. Scleral inflammation was significantly higher at suture sites with polyglactin 910 compared with plain gut at 1 week (P = .004) and 1 month (P < .001).

No eyes experienced wound leaks or other postop complications. – by Robert Linnehan

Disclosures: The authors report no relevant financial disclosures.