January 22, 2018
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No change in retinal thickness observed after Alpha IMS implantation

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No significant changes in retinal structure and thickness were seen in patients after subretinal implantation of the Alpha IMS.

Researchers analyzed 27 patients who received the Alpha IMS (Retina Implant AG). They used the distance tool of the built-in spectral domain OCT software to measure retinal thickness. Three thickness measurements were made in the four quadrants of the retina on the microchip within 6 weeks and 6 months after implantation, according to the study.

The change in retinal thickness from 6 weeks to 6 months after implantation in all four quadrants was not statistically significant. The change for all four quadrants combined was 24 µm ± 68 µm.

Location, time and their interaction were also measured, and none of them had a statistically significant effect on the mean retinal thickness.

“With more patients receiving subretinal implants and with advanced OCT technology, the data set will be extended to study possible changes in retinal structure in finer detail,” the researchers wrote. – by Robert Linnehan

Disclosures: Kuehlewein reports she received financial support from Retina Implant AG during the conduct of the study. Please see the study for all other authors’ relevant financial disclosures.