OCT-Leakage maps identify location of retinal, subretinal fluid

Issue: August 10, 2017

In a prospective cohort series, OCT-Leakage maps were able to identify the location and amount of retinal and subretinal fluid in eyes with a variety of retinal diseases.

Researchers analyzed 12 eyes with retinal edema from various retinal diseases. These eyes were compared with 41 eyes of 24 healthy controls.

Using a novel OCT-Leakage algorithm, maps were developed based on sites of low optical reflectivity. Using the maps, the locations of intraretinal and subretinal fluid were identified. The fluid leakage locations coincided with the location of the sites of fluorescein leakage seen on fluorescein angiography and the location of vascular abnormalities seen with OCT angiography.

“Fluid area and location are difficult to identify well in classic OCT images. OCT-Leakage maps help identify and characterize the fluid extension, quantification and change over time. OCT-Leakage maps have the potential to become a reliable marker of disease activity such as in neovascular AMD, and thus may offer relevant information to complement OCTA,” the researchers wrote. – by Robert Linnehan

Disclosures: Farinha reports no relevant financial disclosures. Please see the study for all other authors’ relevant financial disclosures.

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Source:

Farinha C, et al. Ophthalmology Retina. 2017;doi:10.1016/j.oret.2017.03.004.