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Study: Location of LPI not associated with dysphotopsias

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CORONADO, Calif. — New dysphotopsias occurred commonly after laser peripheral iridotomy, although location was not a statistically significant association, according to a study presented here.

“Overall there was a high rate of new dysphotopsias in our study, 9%, but we also have to keep in mind that there was also a high rate of dysphotopsias before LPI and also a high rate of resolution of dysphotopsias,” Nazlee Zebardast, MD, said at the American Glaucoma Society meeting.

Nazlee Zebardast

Zebardast and colleagues undertook to determine whether location of LPI, superior or nasal/temporal, influenced the occurrence of postoperative dysphotopsias in patients with primary angle closure, primary angle closure suspects and patients with primary angle closure glaucoma. Patients were randomized to undergo superior LPI (285 patients) or nasal/temporal LPI (274 patients). Groups were matched for age, gender and diagnosis. Whereas there were statistically significantly greater numbers of shots and total laser energy dispensed in the superior LPI group (P = .006 and P < .001), there was no postoperative difference in anterior chamber reaction or LPI area treated, Zebardast said.

Before LPI, there was an overall rate of 14.9% of patients reporting incidence of dysphotopsia, with halos, lines, glare and blurring being the most commonly reported symptoms, although the rate of reporting was not significantly different between the groups, she said.

“Interestingly, after LPI, about 12% of subjects reported resolution of one or more dysphotopsia symptoms,” Zebardast said. However, when looking at the occurrence of new-onset dysphotopsias postoperatively, there was no statistically significant difference in location of LPI, with the overall rate being 8.9% for both groups, she said. – by Patricia Nale, ELS

Reference:

Zebardast N. Comparison of new visual disturbances after superior vs. nasal/temporal laser peripheral iridotomy: A prospective randomized trial. Presented at: American Glaucoma Society annual meeting; March 2-5, 2017; Coronado, Calif.

Disclosure: Zebardast reports no relevant financial disclosures.