No correlation seen between IOP, central corneal thickness in premature low birthweight infants

Researchers did not find a correlation between IOP and central corneal thickness in premature low birthweight infants, but they did find both IOP and CCT measurements to be greater than those seen in adults, according to a study.

The study was intended to develop normative data on IOP and CCT measurements in premature low birthweight infants. Ninety eyes of 45 infants born at a mean of 28 weeks’ gestational age and weighing a mean 1,131.5 g underwent a series of ophthalmological examinations, starting at gestational age of at least 30 weeks or within 4 weeks of birth.

A Tono-Pen XL tonometer (Reichert) was used to measure IOP, and a hand-held portable Pachmate DGH 55 pachymeter (DGH Technology) was used to measure CCT.

Mean IOP was 29 mm Hg. Mean corrected IOP was 22.8 mm Hg, with a correction factor of 2.5 mm Hg for each 50 µm change in CCT. Mean CCT was 660 µm in 40 infants who underwent the measurement.

“The IOP and CCT measurements inversely correlate with [gestational ages], but there was no correlation between IOP and CCT in premature [low birthweight] infants,” the researchers wrote.

Disclosure: The authors report no relevant financial disclosures.

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Source:

Grover S, et al. J Pediatr Ophthalmol Strabismus. 2016;doi:10.3928/01913913-20160629-03.