Risks identified for early corneal haze after myopic PRK

Older age was found to be protective against early corneal haze development, while myopia and astigmatism were both associated with increased severity of haze after myopic PRK in an Asian population, according to a study.

The retrospective case series included data from 347 eyes of 177 patients 3 months after undergoing myopic PRK. All of the patients in the study were Asian, the majority of which were Chinese and men.

One hundred eighty-seven eyes had no corneal haze, 76 eyes had a haze grade of more than 0 and less than 1, 76 eyes had a haze grade of 1 or more and less than 2, and eight eyes had a haze grade of 2.

Researchers used a multivariate ordinal logistic regression analysis and found a higher degree of myopia and astigmatism was associated with an increased severity of haze. Additionally, older age protected against the development of corneal haze.

“We show that with appropriate inclusion criteria, PRK is a safe, predictable and efficacious method of treating low to moderate myopia in an Asian population. The risk for early postoperative corneal haze was increased in younger patients and in patients with higher degrees of preoperative myopia and astigmatism,” the study authors said. – by Robert Linnehan

Disclosure: The authors report no relevant financial disclosures.

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Source:

Ang BCH, et al. J Cataract Refract Surg. 2016;doi:10.1016/j.jcrs.2016.01.047.