Phaco alone and with viscogonioplasty may result in similar IOP reductions

Issue: January 10, 2016

Combined phacoemulsification-viscogonioplasty and phacoemulsification alone may have the same effects on long-term IOP in primary angle-closure glaucoma, according to a study.

The prospective randomized clinical trial evaluated 46 eyes that underwent phacoemulsification alone vs. 45 eyes that underwent combined phacoemulsification and viscogonioplasty (VGP) to compare long-term IOP in primary angle-closure glaucoma patients.

Phaco alone reduced mean IOP by 37%, from 22.3 ± 6.3 mm Hg at baseline to 14 ± 3.7 mm Hg at 1 year, while phaco-VGP reduced mean IOP by 38%, from 23.3 ± 7.3 mm Hg at baseline to 14.5 ± 2.5 mm Hg at 1 year (both P < .001).

There was no statistical difference between the two groups in IOP reduction and the number of medications at all follow-up points.

At the final follow-up, there was a significant reduction in the mean extent of synechial angle closure for both groups (P < .001), but the amount of change in peripheral anterior synechiae in the phaco-VGP group was significantly greater than in the phaco-only group (P = .004).

There was an improvement in angle width in both groups (P < .001).

Postoperative trabecular-iris space area increased significantly in both groups, but the amount of the increase was significantly higher in the phaco-VGP group.

Multivariable regression showed that preoperative IOP and female sex were associated with IOP changes at 1 year. – by Kristie L. Kahl

Disclosure: The authors report no relevant financial disclosures.

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Source:

Moghimi S, et al. J Glaucoma. 2015;doi:10.1097/IJG.0000000000000196.