This article is more than 5 years old. Information may no longer be current.
African ancestry, hypertension associated with increased IOP in Latinos
Click Here to Manage Email Alerts
African ancestry and hypertension were found to be risk factors for increased IOP in Latinos, according to a study.
Using data from the population-based Los Angeles Latino Eye Study, researchers estimated genetic ancestry of 3,541 participants. Mean age of participants was 54.9 years, and 40.6% of participants were men.
Average proportion of African ancestry in participants was 3.1% and mean IOP was 14.6 mm Hg.
After adjusting for covariates of age, gender, body mass index, systolic blood pressure, central corneal thickness, type 2 diabetes, smoking status and income, African ancestry remained significantly associated with increased IOP (P =.0005). For every 1% increase in proportion of African ancestry, there was a 0.033 mm Hg increase in IOP; in hypertensive individuals, a three-fold increase in IOP was seen (0.105 mm Hg; P = .008).
“Taken together, Latinos with a high percent of African ancestry, and who also have hypertension, may be at risk for increased IOP and, potentially, a higher risk of glaucoma,” the researchers wrote. – by Kate Sherrer
Disclosure: The authors report no relevant financial relationships.
Collapse
Nannin, et al. Ophthalmology. 2015;doi:10.1016/j.ophtha.2015.08.042.
Click Here to Manage Email Alerts