Issue: January 2016
December 28, 2015
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PDEK with glued IOL, pupilloplasty may be effective for endothelial decompensation

Issue: January 2016
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The combination of glue-assisted intrascleral IOL fixation with pupilloplasty and pre-Descemet’s endothelial keratoplasty may be effective in some cases of endothelial decompensation, according to a study.

Five eyes underwent the single-stage procedure, in which glued IOL fixation was performed to secure the IOL before pupilloplasty was done to stabilize the anterior chamber and prevent air diversion into the vitreous cavity. PDEK was then performed.

“The advantage with a one-stage procedure is that the patient follows a single fixed protocol of postoperative drug regimen and undergoes fewer follow-ups as compared with a staged method,” the study authors said.

Mean graft size was 7.6 ± 0.4 mm, with donor age ranging from 9 months to 65 years.

Mean endothelial cell count was reduced from 2,788 ± 204 cells/mm2 preoperatively to 1,898 ± 90 cells/mm2, averaging a loss of 32 ± 2.8% at 1 month postoperatively.

Postoperatively, mean uncorrected visual acuity was 0.14 ± 0.1 and mean best corrected visual acuity was 0.33 ± 0.2, with no loss of BCVA in any case. Both changes were significant compared with baseline.

IOL decentration and graft failure did not occur in the follow-up period. – by Kristie L. Kahl

Disclosure: The authors report no relevant financial disclosures.