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Hydrophobic acrylic IOL associated with increase in PCO up to 3 years
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A single-piece hydrophobic acrylic IOL was associated with a significant increase in posterior capsule opacification up to 3 years and stabilization between 3 years and 5 years, according to a study.
The prospective study included 390 eyes of 390 patients who underwent phacoemulsification and implantation of an AcrySof SN60AT IOL (Alcon).
Follow-up examinations were performed at 1 month and 1 year, 3 years and 5 years postoperatively. Mean follow-up was 59.6 months.
The main outcome measure was PCO development and the influence of a total or partial anterior capsule cover on the IOL optic within the capsulorrhexis margin and central 3-mm optic area.
In both the total and partial anterior capsule cover groups, PCO in the capsulorrhexis margin and central 3-mm optic area increased significantly from 1 month to 1 year and from 1 year to 3 years (both P < .001) but did not change significantly from 3 years to 5 years.
PCO scores and area in the capsulorrhexis margin were significantly lower in the anterior capsule cover group than in the partial cover group.
In the total capsule cover group, absolute change in PCO area was 4.22% from 1 month to 1 year, 7.06% from 1 year to 3 years, and 1.62% from 3 years to 5 years.
In the partial capsule cover group, absolute change in PCO area was 7.77% from 1 month to 1 year, 8.74% from 1 year to 3 years, and 2.28% from 3 years to 5 years.
Nd:YAG laser capsulotomy was performed in three patients at 1 year and six patients between 1 year and 3 years. – by Matt Hasson
Disclosure: Praveen reports no relevant financial disclosures. See the full study for a list of all authors’ relevant financial disclosures.
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Praveen MR, et al. Am J Ophthalmol. 2015;doi:10.1016/j.ajo.2015.05.037.
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