This article is more than 5 years old. Information may no longer be current.
SANDE questionnaire may offer fast, reliable assessment of dry eye symptoms
The Symptom Assessment in Dry Eye questionnaire may be quick and equally efficacious in scoring dry eye symptoms compared with the Ocular Surface Disease Index, according to a study.
In the clinic-based evaluation, the Ocular Surface Disease Index (OSDI) and Symptom Assessment in Dry Eye (SANDE) questionnaires were given to 114 patients with dry eye disease to correlate and analyze scores from baseline and follow-up visits.
The OSDI score ranges from 0 to 100 and is calculated by the sum of the scores for all 12 questions answered multiplied by 100, which is divided by the total number of questions answered times four. The two-item SANDE questionnaire score is calculated by multiplying the frequency of symptoms score with the severity of symptoms score and obtaining the square root.
At the baseline visit, the mean score was 63.48 ± 23.49 for SANDE and 48.9 ± 22.42 for OSDI. At the follow-up, the mean score was 52.1 ± 24 for SANDE and 43.25 ± 22.9 for OSDI.
Scores were significantly correlated between the two questionnaires at baseline (P < .001) and between changes in scores from baseline to follow-up (P < .001).
Bland-Altman analysis found a clinical difference of –1.5 units at baseline between the SANDE and OSDI questionnaires and 1.8 units at the follow-up.
“In this regard, the SANDE questionnaire seems to hold promise as a quick and valid method for evaluating the frequency and severity of symptoms of patients with [dry eye disease],” the study authors said. – by Kristie L. Kahl
Disclosure: Amparo reports no relevant financial disclosures. Please see the full study for a list of all other authors’ relevant financial disclosures.
Collapse
Amparo F, et al. Ophthalmology. 2015:doi:10.1016/j.ophtha.2015.02.037.