January 18, 2015
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‘Intriguing’ anterior segment studies have impact

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WAILEA, Hawaii – Among this year’s “most intriguing” manuscripts published in OphthalmologyMarjan Farid, MD, presented three impactful anterior segment studies involving large cohorts at the Hawaiian Eye 2015 meeting.

Marjan
Farid

In a study of almost 175,000 eyes, “Factors That Influence Intraocular Pressure Changes after Myopic and Hyperopic LASIK and Photorefractive Keratectomy” found postoperative IOP decreased in four groups of patients, those undergoing myopic LASIK, myopic PRK, hyperopic LASIK and hyperopic PRK.

“LASIK patients had a greater drop in intraocular pressure, probably due to changes in the flap and the biomechanical changes from that,” she said. Higher myopic corrections can have a dramatic effect on pressure, as well.

“The Effect of Donor Diabetes History on Graft Failure and Endothelial Cell Density 10 Years after Penetrating Keratoplasty” used data from the Cornea Donor Study, which looked at more than 1,000 patients who had received corneal grafts for endothelial disease.

“Essentially over a 10-year graft survival, donor diabetes did not make a difference in terms of the graft survival,” she said. “These findings are reassuring that we are able to use those corneas in penetrating keratoplasties.”

In the article “Long-Term Physical Activity and Risk of Age-related Cataract,” two large cohorts including more than 52,000 participants between 45 and 83 years old were assessed for the relationship between cataract development and physical activity. The analysis found that with every hour of moderate effort of physical activity, the risk for cataract decreased 5%; heavy manual labor decreased the risk by 16% and more than 6 hours per day of leisure time inactivity increased the risk by 27%.

“So next time your patients ask you, ‘Doctor what can I do to decrease my risk of cataract surgery?’, [tell them] ‘Get up and start moving,’” Farid said. – by Patricia Nale

References:

Schallhorn JM, et al. Ophthalmology. 2014;doi:10.1016/j.ophtha.2014.09.033.

Lass JH, et al. Ophthalmology. 2014;doi:10.1016/j.ophtha.2014.09.012.

Zheng SJ, et al. Ophthalmology. 2014;doi:10.1016/j.ophtha.2014.08.023.

Disclosure: Farid reports no relevant financial disclosures.