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Corneal collagen cross-linking yields long-term stability with post-LASIK ectasia
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In cases with corneal ectasia after LASIK, corneal collagen cross-linking produced long-term stability with no significant side effects, according to study findings.
The retrospective study included 20 eyes with post-LASIK ectasia treated with corneal collagen cross-linking. Main outcome measures of the study were uncorrected (UDVA) and corrected (CDVA) distance visual acuities, spherical and cylindrical refractions, and simulated keratometry (K) values. Mean follow-up was 42 months.
UDVA and CDVA significantly improved from baseline, according to the researchers. Mean UDVA improved from 0.78 LogMAR to 0.53 LogMAR and mean CDVA improved from 0.27 LogMAR to 0.19 LogMAR. Additionally, none of the eyes lost 1 or more Snellen lines of either UDVA or CDVA.
Mean spherical refraction was not significantly different at final follow-up; however, mean cylindrical refraction decreased significantly, according to the researchers.
Maximum K value decreased from 46 D at baseline to 45.6 D at the last visit. By the final follow-up, five eyes had a decrease in maximum K value of 1 D or more, and 15 eyes remained stable.
The researchers observed no serious complications.
Disclosure: The authors have no relevant financial disclosures.
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