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SD-OCT used to evaluate anterior chamber inflammation
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Anterior chamber inflammation can occur after cataract surgery. Slit lamp biomicroscopy has been the conventional method of visualizing the aqueous, but this method is limited because it is subjective. In addition, it is difficult to grade the severity of anterior chamber reaction in corneal edema or opacification. Lowder and associates were the first to visualize the anterior chamber reaction by optical coherence tomography. We were the first to do anterior chamber cell grading in uveitis using time-domain OCT.
Optical coherence tomography
Recently, OCT machines with sophisticated spectral-domain or Fourier-domain optics, which enable examination of both the anterior and posterior segments in a single setup, have been developed. This enables high-definition scanning of the anterior chamber. In SD-OCT, by reading the information of an A-scan simultaneously and analyzing the frequency spectrum of the interference between the reflected light and a stationary reference mirror, scan speed higher than time domain is possible. This permits greater imaging resolution and less distortion caused by patient movements. Moreover, its faster acquisition time enables volume-scanning and three-dimensional reconstruction. We used high-resolution SD-OCT for imaging anterior chamber cells in eyes with postoperative uveitis.
Technique
Cirrus HD-OCT (Carl Zeiss Meditec) imaging of the anterior chamber was performed on the first postoperative day. OCT images were taken with the patient in the sitting position. Anterior segment raster scan mode was used to visualize the anterior chamber.
Click here to read the full publication exclusive, Complications Consult, published in Ocular Surgery News APAO Edition, October 2014.