This article is more than 5 years old. Information may no longer be current.
SD-OCT helps predict response to VEGF therapy in patients with RVO
Click Here to Manage Email Alerts
SAN DIEGO — Baseline visual acuity and features of the outer retina seen on spectral-domain optical coherence tomography can help predict final visual outcome in patients with macular edema secondary to retinal vein occlusion, according to a speaker here.
“Despite complete resolution of macular edema, some patients still have a poor visual outcome,” Hector H. Hernandez-Torres, MD, said at the American Society of Retina Specialists annual meeting. “Macular thickness is only one of several factors that affect visual acuity.”
Hector H. Hernandez-Torres
Hernandez-Torres and colleagues undertook a retrospective review of 60 patients treated with at least three intravitreal anti-VEGF injections for macular edema secondary to retinal vein occlusion. All patients underwent a complete ophthalmologic examination, including best corrected visual acuity, applanation tonometry, slit lamp biomicroscopy, fluorescein angiography, fundus autofluorescence, spectral-domain OCT (SD-OCT) and dilated fundus examination at baseline, 3 months, 6 months and 12 months.
“Not all patients benefit from treatment, and in order to identify these patients and avoid unnecessary treatment, predictors at baseline would be desirable,” he said.
The strongest individual predictor of final BCVA was the integrity of the inner and outer segment/external limiting membrane interface as seen on SD-OCT, he said.
Disclosure: Hernandes-Torres has no relevant financial disclosures.