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Ectasia development associated with percent tissue altered during LASIK
A significant association exists between the development of ectasia in eyes with normal preoperative topography and the percent tissue altered during LASIK, according to a study.
The retrospective, case control study included 30 eyes of 16 patients who developed post-LASIK ectasia and 174 eyes of 88 patients with uncomplicated LASIK and at least 3 years of follow-up. Researchers evaluated the patients’ age, preoperative central corneal thickness, residual stromal bed, Ectasia Risk Score System scores and percent tissue altered.
Among patients in the ectasia group, percent tissue altered of 40 or greater was the most prevalent factor in ectasia development (97%), followed by age younger than 30 years (63%), residual stromal bed smaller than 300 µm (57%) and an ectasia risk score of 3 or greater (43%). According to the researchers, percent tissue altered of 40 or greater had the highest odds ratio.
In a stepwise logistic regression analysis, the researchers also found percent tissue altered of 40 or greater to be the single most significant independent variable among patients who developed ectasia.
Disclosure: The authors have no relevant financial disclosures.