July 28, 2014
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Boston type 1 keratoprosthesis produced favorable long-term outcomes

Despite an increase in complications with longer follow-up, Boston type 1 keratoprosthesis was shown to have lasting positive effects during a 7-year period, according to study findings.

The retrospective study included 139 eyes of 133 patients who underwent Boston type 1 keratoprosthesis (KPro) implantation at five tertiary referral centers. Researchers analyzed visual acuity, postoperative complications and device retention outcomes for patients with at least one postoperative visit. Mean follow-up was 46.7 months.

Prior to undergoing KPro, only 10.8% of patients had a VA of 20/200 or better. VA improved to 20/200 or better in 70% of patients postoperatively, with a probability of 50% that these improvements would be maintained at 7-year follow-up.

The estimated retention rate for the device at 7 years was 67%, according to the researchers.

Among the postoperative complications reported, 7-year cumulative incidence was 49.7% for retroprosthetic membrane formation, 21.6% for glaucoma surgery, 18.6% for retinal detachment and 15.5% for endophthalmitis.

Disclosure: See the study for full list of all authors’ relevant financial disclosures.