July 11, 2014
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Eye scanner accurately identifies strabismus, amblyopia in preschool children

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A new eye scanner identified strabismus and/or amblyopia in preschool-aged children more accurately than a widely-used autorefractor, according to study findings.

The study included 300 children who underwent screening with the Pediatric Vision Scanner (PVS; REBIScan) and the SureSight AutoRefractor (Welch Allyn) at two centers.

The authors assessed sensitivity and specificity of the PVS in detecting strabismus and/or amblyopia, as well as the positive and negative likelihood ratios in identifying those conditions, in comparison with the SureSight.

Results showed 188 patients (62.6%) had strabismus only, amblyopia only or both; 112 patients (37.3%) had neither strabismus nor amblyopia.

The PVS demonstrated significantly higher sensitivity in detecting strabismus and amblyopia compared with the SureSight, according to the researchers (0.97 vs. 0.74). Detection specificity was also significantly higher in the PVS (0.87 vs. 0.62).

False-positive readings for strabismus or amblyopia were 12.6% for the PVS scanner and 38.4% for the SureSight Autorefractor.

Positive likelihood ratios, which denoted the likelihood that a child had strabismus or amblyopia, were 7.7 for the PVS and 1.9 for the SureSight Autorefractor.

Negative likelihood ratios, which indicated the probability that screening would miss children with strabismus or amblyopia, were 0.03 for the PVS and 0.42 for the SureSight Autorefractor.

Disclosure: The authors have no relevant financial disclosures.