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Recurrent corneal erosion syndrome linked to various causative factors
Recurrent corneal erosion syndrome was attributed to diverse etiologies and presented in several locations, according to a study.
“Interestingly, a significant number of [recurrent corneal erosion syndrome] patients begin to manifest the syndrome after keratorefractive surgery, and a high percentage of patients also present with [meibomian gland dysfunction],” the study authors wrote.
The retrospective study included 117 eyes of 100 patients diagnosed with recurrent corneal erosion syndrome (RCES). Mean patient age was 44.5 years. The investigators studied demographic data, disease etiology, corneal location and association with meibomian gland dysfunction.
Seventeen patients had bilateral RCES; it was also identified in 56 right eyes and 61 left eyes.
RCES was attributed to previous minor trauma in 46 eyes (39.3%), epithelial basement membrane corneal dystrophy in 20 eyes (17.1%), photorefractive keratectomy in 20 eyes (17.1%), LASIK in nine eyes (7.7%) and unknown causes in 22 eyes (18.8%).
The most commonly found sites of RCES were in the inferior paracentral cornea (68.4%), upper cornea (21.3%) and widespread location (21.3%).
Patients with RCES after laser refractive surgery had no signs or symptoms of dry eye and had normal Schirmer test scores and corneal sensitivity.
Meibomian gland dysfunction was identified in 59 patients (59%); 75% of patients with spontaneous RCES also presented with meibomian gland dysfunction, the authors said.
Disclosure: The authors have no relevant financial disclosures.