February 26, 2014
1 min read
Save

Glaucoma filtration device, trabeculectomy similarly successful at 2 years

You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com.

A glaucoma filtration device and trabeculectomy yielded similar clinical and visual results at 2 years, according to a study.

Perspective from Douglas J. Rhee, MD

The prospective randomized multicenter trial included 120 eyes of 120 patients; 59 eyes were treated with the Ex-Press device (Alcon) and 61 eyes underwent trabeculectomy.

Patients in both groups were followed for 2 years after surgery. Surgical success was defined as IOP of 5 mm Hg to 18 mm Hg with or without medications and without additional glaucoma surgery.

Baseline logMAR visual acuity was 0.3 in the Ex-Press group and 0.25 in the trabeculectomy group. Postoperative visual acuity was 0.28 in the Ex-Press group and 0.37 in the trabeculectomy group at 2 years.

Mean visual acuity decreased significantly in both groups at 1 day but recovered at 1 month in the Ex-Press group and 3 months in the trabeculectomy group.

Mean IOP decreased from 25.1 mm Hg at baseline to 14.7 mm Hg in the Ex-Press group and from 26.4 mm Hg to 14.6 mm Hg in the trabeculectomy group. The decrease in IOP was statistically significant in both groups (P < .001).
Medication use decreased significantly in both groups at 2 years (P < .001).

The 2-year success rate was 83% in the Ex-Press group and 79% in the trabeculectomy group.

Disclosure: See the study for a full list of all authors’ relevant financial disclosures.