February 06, 2014
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Femtosecond thin-flap LASIK effective in eyes with thin corneas, normal topography
Femtosecond laser thin-flap LASIK yielded similar visual and anatomic outcomes in eyes with thin corneas and normal topography, according to a study.
The retrospective study included 291 eyes of 146 patients with a central corneal thickness of less than 500 µm and normal topography. A control group included 371 eyes of 193 patients with a central corneal thickness of 500 µm or greater.
Outcomes were evaluated 3 to 6 years after surgery in the thin cornea group and 3 to 4 years after surgery in the comparator group.
At final follow-up, mean uncorrected distance visual acuity was –0.10 in the thin cornea group and –0.12 in the control group. Corrected distance visual acuity was –0.18 in the thin cornea group and –0.19 in the control group. Manifest refraction spherical equivalent was –0.13 in the thin cornea group and –0.10 in the control group.
At final follow-up, uncorrected distance visual acuity was 0.00 or better in 180 eyes in the thin cornea group (86.5%) and 319 eyes in the control group (86%). Corrected distance visual acuity was 0.00 or better in 207 eyes in the thin cornea group (99.5%) and 371 eyes in the control group (100%).
No eyes in either group had signs of corneal ectasia at final follow-up.
Disclosure: The authors have no relevant financial disclosures.
Perspective
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J. Bradley Randleman, MD
The authors report good news, that LASIK appeared stable in their population of patients with “thin” corneas (below 500 μm) for at least 3 years postoperatively. This provides further evidence that no absolute cut-offs likely exist for screening parameters, but rather that risk exists on a continuum depending on a variety of factors. The authors also reinforce the need for in-depth screening of corneal parameters, including topographic and tomographic findings. These findings support previous work demonstrating that a variety of potential individual risk factors should be taken into account when assessing risk for postoperative ectasia.
It is difficult to draw more detailed conclusions than these because the patient variables are reported as aggregate averages and ranges rather than as individual metrics that could be more thoroughly evaluated for each patient. While these variables follow generally conservative ranges, there appears to be some outliers in thickness, residual bed and topographic patterns that warrant further investigation.
Recent research has addressed the percentage of tissue altered at the time of LASIK (flap thickness and tissue ablated); this may prove to be a more sensitive metric than central corneal thickness or residual stromal bed thickness as it more directly accounts for the probably biomechanical alteration for an individual cornea at the time of LASIK in eyes with normal topographic evaluations. This paper would seem to at least indirectly support that concept.
J. Bradley Randleman, MD
Editor in Chief, Journal of Refractive Surgery
Disclosures: Randleman has no relevant financial disclosures.
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