July 17, 2013
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Keratoconic eyes have more inter-eye asymmetry than normal eyes

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Subjects with keratoconus have greater inter-eye asymmetry regarding pachymetry and posterior corneal elevation than subjects with normal corneas, according to a study.

The prospective study included 302 eyes of 151 subjects; 98 subjects had bilateral keratoconus, and 53 subjects had bilateral normal corneas. The Pentacam (Oculus) was used to measure posterior elevation at the thinnest point of the cornea (PETP), pachymetry at the thinnest point of the cornea (TP), central corneal thickness (CCT), distance, volume and differential pachymetry.

Mean inter-eye asymmetries of normal subjects for CCT, TP and PETP were 10.28 µm, 11.04 µm and 3.75 µm, respectively. For keratoconic subjects, CCT, TP and PETP were 25.89 µm, 30.15 µm and 20.08 µm, respectively.

The differences between keratoconic eyes and normal eyes were statistically significant for all variables (P < .05).