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Patients prefer morning administration of glaucoma medication
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Patients adhered to morning administration of once-daily glaucoma medication slightly better than evening administration, according to a study.
The prospective, randomized study included 30 patients who were newly diagnosed with glaucoma or ocular hypertension. Patients began taking travoprost eye drops and were randomized to morning or evening administration for 1 month and then switched to the opposite dosing schedule for another month.
An automatic dosing aid was used to monitor adherence. Patients also answered a three-item questionnaire on dosing time preference and self-reported adherence.
Study results showed overall adherence of 89.3%. Adherence to morning dosing was 90.9% and adherence to evening dosing was 87.3%. The difference was statistically insignificant.
Men were more adherent to morning dosing than evening dosing (P = .039). Adherence among women was similar in the morning and evening.
Overall adherence was 91.7% in the first month and 86.5% in the second month. A majority of patients expressed a preference for morning dosing, the authors said.
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