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Cycloplegia with atropine may increase hyperopic shift, ocular higher-order aberrations
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A significant hyperopic shift and an increase in ocular higher-order aberrations may occur in children after cycloplegia with topical atropine, according to a study.
The prospective noncomparative study included 23 eyes of 23 subjects with hyperopia. All subjects were aged 3 years to 12 years.
Cycloplegia with 1% topical atropine solution was administered twice daily for 1 week. Refraction, ocular higher-order aberrations and corneal higher-order aberrations were measured before and after treatment.
Spherical equivalent refraction increased significantly from +1.92 D to +3.10 D (P < .01) after 1 week of treatment.
Coma-like aberrations increased significantly from 0.282 µm to 0.316 µm (P = .02), spherical-like aberrations increased significantly from 0.169 µm to 0.192 µm (P = .02), and total higher-order aberrations increased significantly from 0.333 µm to 0.377 µm (P = .01).
Corneal higher-order aberrations did not change after treatment.
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