This article is more than 5 years old. Information may no longer be current.
Valve implant linked to reduced endothelial cell density in inflammatory glaucoma
Click Here to Manage Email Alerts
Glaucoma valve implantation was associated with diminished endothelial cell density in children with uveitic glaucoma, according to a study.
The cross-sectional case study included 80 eyes of 42 patients diagnosed with uveitis before the age of 16. The study group comprised 28 eyes that received an Ahmed glaucoma valve (New World Medical). A control group included 52 eyes without valve implants. Mean patient age was 16.7 years in the study group and 12.7 years in the comparator group.
Investigators used a non-contact specular microscope to assess endothelial cell density in the central corneal zone.
The mean follow-up interval after implantation in the study group was 3.5 years. Mean duration of uveitis was 12 years in the study group and 7.4 years in the control group.
Study results showed that endothelial cell density was 2,359 cells/mms in the study group compared to 3,088 cells/mm2 in the control group (P < .001).
Reduced endothelial cell density also correlated with previous intraocular surgery, age, duration of uveitis and corneal touch, the authors said.
Click Here to Manage Email Alerts