April 19, 2013
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Prevention of posterior segment complications critical in keratoprosthesis patients

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The significant prevalence of posterior segment complications following keratoprosthesis surgery, coupled with the subsequent anatomic difficulties correlated with their management, has made understanding and prevention of these postoperative complications crucial, according to a study.

The retrospective chart review included 98 eyes of 94 patients who underwent implantation of a Boston type 1 keratoprosthesis by a single surgeon over a 6-year period.

Patients’ mean age was 62.8 years. A mean follow-up of 28.2 months was attainable for 83 eyes.

The mean time to onset for any posterior segment postoperative complications was 5.6 months, according to the authors.

At least one postoperative posterior segment complication occurred in 38 of the 83 eyes, of which retinal detachmentchoroidal detachment and sterile vitritis were most common.

By the final follow-up, 63% percent of eyes had corrected distance visual acuity of 20/200 or better. However, corrected distance visual acuity worsened at postoperative follow-up visits in eyes affected by posterior segment complications compared with those that were unaffected, with a final logMar 1.45 vs. 0.89, respectively (P = .003).