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Lamellar macular hole linked to reduced visual acuity, central retinal sensitivity
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Lamellar macular hole was associated with diminished macular function partly related to the depth of the hole, according to a study. Impaired function was more severe in eyes with abnormalities of the outer retinal layers.
The cross-sectional observational study included 39 eyes of 37 patients diagnosed with lamellar macular hole. A comparator group comprised 20 age-matched controls.
Investigators evaluated logMAR best corrected visual acuity, microperimetry, depth and thickness of lamellar macular holes, and anatomic vitreoretinal relationships.
The lamellar macular hole group had significantly lower mean total and mean central retinal sensitivity compared with controls (both P < .0001). BCVA was 0.15 in the lamellar macular hole group and 0.03 in the control group (P < .0001).
Central retinal thickness was 329 µm in the lamellar macular hole group and 265 µm in the control group (P < .0001).
There was a modest relationship between mean total and central retinal sensitivity and lamellar macular hole depth (P = .006 and P = .02, respectively).
Focal interruptions of the inner-outer segment junction were associated with lower BCVA and macular sensitivity in 38% of eyes in the lamellar macular hole group, the authors said.
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