March 14, 2013
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One-piece, three-piece MICS IOLs yield similar amounts of PCO at 1 year

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One-piece and three-piece microincision IOLs caused similar amounts of posterior capsular opacification, but the one-piece implant led to significantly fewer capsular folds, according to a study.

 The prospective, randomized study included 80 eyes of 40 patients with age-related cataract who underwent phacoemulsification and received a one-piece AF-1 NY-60 MICS IOL (Hoya) in one eye and a three-piece AF-1 iMICS Y-60H IOL (Hoya) in the contralateral eye.

One year after surgery, investigators assessed uncorrected and best corrected visual acuity, PCO, IOL position and centration, and rhexis-IOL overlap. A three-point scale was used to grade the amount of PCO and posterior fibrosis. The need for Nd:YAG capsulotomy was also recorded.

Study results showed that mean objective PCO scores were 0.2 in the one-piece IOL group and 0.3 in the three-piece IOL group; the between-group difference was statistically insignificant. Both groups also had similar UCVA and BCVA.

Both groups had similar Nd:YAG capsulotomy rates. The three-piece IOL group had a significantly higher incidence of capsular folds than the one-piece IOL group (P = .02), the authors said.