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Enhanced depth imaging shows choroidal thinning in retinitis pigmentosa
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Enhanced depth imaging with spectral domain optical coherence tomography provided in vivo evidence of reduced submacular choroidal thickness in retinitis pigmentosa patients, according to a study.
The study included 21 patients with retinitis pigmentosa and a control group of 25 healthy age-matched participants with similar refractive error and no retinal or glaucomatous disease who underwent retinal and choroidal imaging using the Spectralis HRA+OCT (Heidelberg Engineering)
Measurements were taken subfoveally and at 500-µm intervals for 2.5 mm nasal and temporal to the center of the fovea. Choroidal thickness was compared at each location between groups. Investigators also calculated associations between choroidal thickness, Snellen best corrected visual acuity and central retinal thickness.
Results showed that mean choroidal thickness was 245.6 µm in retinitis pigmentosa patients and 337.8 µm in the control subjects. The difference was statistically significant (P < .0001). When compared with the control group, visual acuity and retinal thickness did not correlate with subfoveal choroidal thickness in retinitis pigmentosa patients.
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