January 31, 2013
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Perfluoropropane injection offers alternative treatment for vitreomacular traction

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Intravitreal expansile perfluoropropane injection may be a minimally invasive alternative to pars plana vitrectomy in treatment of vitreomacular traction, according to a study.

The retrospective, interventional case series included 15 eyes of 14 patients with symptomatic, persistent vitreomacular traction who received intravitreal injection of 0.3 mL 100% perfluoropropane.

Study results showed resolution of vitreomacular traction in six eyes 1 month after treatment. Within 6 months, three additional eyes experienced vitreomacular traction release and four eyes underwent pars plana vitrectomy. Further surgery was declined in two eyes.

Foveal contour was completely restored in seven of the nine eyes with vitreomacular traction release. Mean maximum foveal thickness decreased by 65.8 µm at 1 month, which was statistically significant (P = .041). There were no significant changes in central foveal thickness or visual acuity.

Eyes that had less vitreomacular traction, low vitreous face reflectivity and a maximum foveal thickness of less than 500 µm before treatment experienced resolution of vitreomacular traction within 1 month.