January 11, 2013
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Graves' disease linked with thin retinal nerve fiber layer

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Patients with Graves’ disease may have a thinner retinal nerve fiber layer than healthy eyes, according to a study.

The study included 65 patients with Graves’ disease and 54 age-matched and sex-matched controls. The Heidelberg Retina Tomograph III was used to perform an optic nerve head analysis on all subjects.

Mean IOP of Graves’ disease patients was 14.6 ± 2.9 mm Hg, and mean IOP of the controls was 13.4 ± 2.1 mm Hg (P = .01).

Mean retinal nerve fiber layer thickness was lower in Graves’ disease patients (0.25 ± 0.06 mm) than in the control group (0.31 ± 0.08 mm), which was statistically significant (P = .02).

The mean retinal nerve fiber layer cross-sectional area was less in Graves’ disease patients (1.30 ± 0.32 mm2) than in the control group (1.52 ± 0.43 mm2), which was statistically significant (P = .03).