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Central visual field defects linked to higher ocular pulse amplitude in normal-tension glaucoma
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Elevated ocular pulse amplitude was associated with centrally located visual field defects in patients with normal-tension glaucoma, according to a study.
There were 100 eyes of 100 subjects in the retrospective study; 54 patients had normal-tension glaucoma and 46 subjects did not have glaucoma.
Glaucoma patients were assigned to two subgroups: a central visual field-invading group and a central visual field-sparing group.
Subjects with IOP lower than 21 mm Hg, normal visual fields, no retinal nerve fiber layer defects or optic disc changes, and no history of systemic or ocular disease were deemed healthy.
Dynamic contour tonometry was used to measure ocular pulse amplitude (OPA) in all subjects.
Study results showed no differences in OPA between glaucoma eyes and healthy eyes.
The central visual field-invading group had an IOP of 14.4 mm Hg and OPA of 2.9 mm Hg. The central visual field-sparing group had an IOP of 12.7 mm Hg and OPA of 2 mm Hg. The between-group differences were statistically significant (P = .025 and P < .001, respectively).
Data showed a significant positive correlation between OPA and visual field test indices indicating central visual field defects (P < .001). There was no such association between IOP and central visual field deficits, the authors said.
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