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Integrity of foveal photoreceptor layer correlates with BCVA, retinal sensitivity
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The morphologic features of the foveal photoreceptor layer correlate with best corrected visual acuity, mean central retinal sensitivity and total retinal sensitivity in patients with lamellar macular hole, a study found.
The prospective, multicenter, observational case series analyzed 54 patients with lamellar macular hole. Forty patients had complete integrity of the inner segment/outer segment (IS/OS) junction and the external limiting membrane line, eight patients had partial or complete disruption of the IS/OS junction with an intact external limiting membrane line, and six patients had an alteration of both the IS/OS junction and external limiting membrane line.
Patients in the first two groups had significantly better mean BCVA, total retinal sensitivity and fixation stability than patients in the last group (both P < .05). There were no differences between the first two groups.
The degree of integrity of the foveal photoreceptor layer was determined to correlate with mean BCVA, mean central retinal sensitivity and total retinal sensitivity (all P < .001).
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