December 28, 2012
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Combined glaucoma procedure yields better results in children than trabeculectomy alone

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Trabeculectomy and combined trabeculotomy-trabeculectomy were similarly effective in children with glaucoma, with the combined procedure sustaining better long-term results, a study found.

Success was “due to less frequent occurrence of failures associated with increased or decreased IOP,” the study authors wrote.

The retrospective, comparative study analyzed 40 eyes of 33 patients with pediatric glaucoma. Seventeen eyes underwent trabeculectomy, and 23 eyes were treated with combined trabeculotomy-trabeculectomy. Intraoperative mitomycin C was used  in all procedures.

Over a mean follow-up of 38.3 months, no significant difference was observed between the two groups in intraocular pressure, but log-rank survival analysis demonstrated a significantly higher success rate from the combined surgical procedure compared with trabeculectomy (P = .027).

Treatment failures included three patients with IOP greater than 21 mm Hg and four with IOP less than 5 mm Hg. No significant differences were seen in complications between the groups.