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NSAID eye drops may reduce pain after intravitreal injection for AMD
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Routine in-office intravitreal injections generally result in mild pain that dissipates within 1 week, but use of NSAID eye drops after injection may further reduce irritation, a study determined.
The prospective study included 40 injection-naïve patients who received routine bevacizumab intravitreal injections for age-related macular degeneration.
Patients were randomized to three groups: no drops, artificial tears or ketorolac tromethamine 0.4% eye drops. Self-reported pain scores were analyzed based on a scale of 0, no distress, to 10, unbearable distress.
Pain was found to last 3 to 7 days after injection. On average, patients using ketorolac drops reported 2.25 days of pain, compared with 3.54 days in the artificial tears group and 5.13 days in the no-drops group (P < .05).
The longest duration of pain reported in the ketorolac group was 3 days, compared to 5 days for the artifical tears group and 7 days for the no-drops group.
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