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Spontaneous venous pulsation weakly associated with POAG
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Spontaneous venous pulsation was detected less frequently in patients with primary open-angle glaucoma than in patients with suspected glaucoma, according to a study.
“Among the patients with POAG, [spontaneous venous pulsation] was less common in patients with low IOP at all stages of disease. These results are consistent with vascular factors having a more significant role in patients with POAG with low IOP than in patients with POAG with higher IOP,” the study authors said.
Investigators examined 229 patients with primary open-angle glaucoma (POAG) and 205 patients with suspected glaucoma. Mean patient age was 57.5 years among patients with POAG and 58.8 years among glaucoma suspects.
The Spectralis HRA confocal scanning laser ophthalmoscope (Heidelberg Engineering) was used to assess spontaneous venous pulsation. Patients with POAG were assigned to three groups based on the frequency distribution of untreated IOP: IOP of 15 mm Hg or less (first group), IOP greater than 15 mm Hg but equal to or less than 21 mm Hg (second group) and IOP greater than 21 mm Hg (third group).
Study results showed that spontaneous venous pulsation occurred significantly more frequently in patients with suspected glaucoma than in those with POAG (P < .0001).
Among patients with POAG, the frequency of spontaneous venous pulsation was 63.9% in the third group, 57.3% in the second group and 40.2% in the first group. The difference between the second and third groups was statistically insignificant.
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