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Study shows similar IOP readings at 6 a.m. and 8 a.m. in supine patients
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IOP readings obtained at 8 a.m. in resting supine patients equaled those taken at 6 a.m. in supine patients awaking from sleep, according to a study.
The study included 50 eyes of 50 normal subjects, glaucoma suspect patients and glaucoma patients; 22 patients were undergoing treatment for glaucoma and 28 patients were not undergoing treatment. Mean patient age was 69 years.
IOP was measured on the same day in the supine position at 6 a.m. upon awaking and before getting up and at 8 a.m. after 30 minutes of rest in the supine position.
Study results showed that mean and median IOP readings were 16.06 mm Hg and 15.5 mm Hg, respectively, at 6 a.m. and 15.94 mm Hg and 15 mm Hg, respectively, at 8 a.m.
The difference between 6 a.m. and 8 a.m. IOP readings was not statistically significant in the population as a whole and in all subgroups. There were also no significant differences between patients with high IOP and those with normal IOP.
“This new strategy for the [diurnal pressure curve] will make it a widely used tool in daily practice since it spares the need for hospitalization or home measurements,” the study author said.
Perspective
Back to TopDouglas J. Rhee, MD
The authors have provided useful information regarding the correlation of early-morning supine IOP (6 a.m.) with the typical first morning in-office IOP time point (8 a.m.) in the supine position. Further research on the significance of diurnal fluctuation will hopefully result in our ability to identify patients at greater risk for disease progression.
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