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HD-OCT may cause errors in neuroretinal rim measurement
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High-definition optical coherence tomography yielded errors in neuroretinal rim measurement in myopic eyes, especially those with parapapillary atrophy, higher myopia, greater axial length, vitreous opacity or acute cup slope angle, according to a study.
“These findings should be considered when interpreting neuroretinal rim thickness measured by Cirrus HD-OCT,” the study authors said.
The study measured neuroretinal rim thickness of 255 myopic eyes with Cirrus HD-OCT (Carl Zeiss Meditec), then analyzed 72 cross-sectional optic nerve head images obtained at 5° intervals to assess the prevalence of optic disc margin and cup margin detection errors.
Neuroretinal rim measurement errors were detected in 17.6% of eyes (45 eyes). Optic disc margin detection errors were found in 11.4% (29 eyes) at the temporal (16 eyes), superior (11 eyes) and inferior (2 eyes) quadrants. Cup margin detection errors were found in 7.5% (19 eyes) at the nasal (17 eyes) and temporal (2 eyes) quadrants. In 1.2% (3 eyes), both disc and cup margin detection errors were found.
The presence of parapapillary atrophy, higher myopia and greater axial length were significantly associated with errors in detection of temporal optic disc margin (P < .001), while vitreous opacities attached to the optic nerve head surface or acute cup slope angles were significantly associated with cup margin detection errors (P < .001).
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