October 29, 2012
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DSAEK may improve visual acuity after failed PK

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Descemet’s stripping automated endothelial keratoplasty may improve vision and lower complication rates if penetrating keratoplasty fails, according to a study.

The retrospective chart review comprised 30 eyes of 30 patients with prior failed PK who later underwent DSAEK. Anatomic success and failure, postoperative complications, lenticle size, visual acuity and IOP change were analyzed in all patients.

Patients were postoperatively examined at 1 day, 1 week and once a month thereafter. All patients had a minimum follow-up of 3 months.

Prior to DSAEK, 25 patients underwent PK once, four patients underwent PK twice, and one patient underwent PK three times.

Primary DSAEK detached in five eyes. One was repaired in the office, two underwent successful repeat DSAEK, and two underwent failed repeat DSAEK before undergoing PK again.

At 3 months, best corrected visual acuity improved in 19 eyes, remained the same in six eyes and worsened in one eye.

“We believe, in the future, it is important for surgeons to begin reporting DSAEK results of anatomic success, vision and complications in the context of the anterior segment anatomy,” the study authors said.