This article is more than 5 years old. Information may no longer be current.
Researchers describe characteristics of CRVO with inflammatory etiology
Clinical characteristics of central retinal vein occlusion with idiopathic inflammatory conditions include its appearance over a broad range of ages and its tendency to respond well to systemic corticosteroid therapy, a study found.
Inflammatory findings appear in about 10% of CRVO cases, the study authors said, and have a male predilection and unknown causative etiology.
The retrospective study reviewed 51 eyes of 48 patients with CRVO to determine if there were inflammatory findings related to retinal vasculitis in the form of severe peripheral retinal vascular changes based on fluorescein angiography and anterior vitreous cells.
Six eyes of five patients had severe vascular leakage and anterior vitreous cells.
No causative etiology was found in any of the five male patients who were diagnosed with ischemic CRVO. Age ranged from 16 years to 68 years.
All five patients received systemic corticosteroid therapy and were followed for a mean of 41.8 months. Mean logMAR visual acuity and central retinal thickness significantly improvement from baseline to final visit (P = .004 and P = .001, respectively).