Issue: February 2013
October 24, 2012
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Anterior chamber IOL effective in patients with chronic uveitis

Issue: February 2013
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Uveitic eyes with inadequate capsule support experienced an improvement in corrected distance visual acuity with anterior chamber IOL implantation, a study found.

There was no significant increase in long-term complications compared with posterior chamber IOL placement.

The retrospective observational cohort study analyzed 36 eyes of 34 patients with a history of chronic uveitis. Eighteen eyes of 18 patients had cataract surgery with anterior chamber IOL implantation, and 18 eyes of 16 patients had cataract surgery with primary in-the-bag posterior chamber IOL implantation.

Corrected distance visual acuity was reviewed preoperatively and at 1, 3 and 6 months and 1, 2, 3 and 4 years postop. Postoperative complications also were reviewed during follow-up.

No significant difference was found in the incidence of postop complications between the groups except for the development of posterior capsule opacification in the posterior chamber IOL group.

Mean logMAR corrected distance visual acuity improved from 1.489 ± 1.07 preop to 0.478 ± 0.533 at 3 years in the anterior chamber IOL group (P = .001) and from 0.506 ± 0.265 preop to 0.247 ± 0.767 at 3 years in the posterior chamber IOL group (P = .010)

“Primary and secondary [anterior chamber] IOL implantation can be considered safe and efficacious in patients with any type of quiescent uveitis,” the study authors said, noting that anterior chamber IOL implantation did not increase the risk of complications and achieved significant improvement in visual acuity.