October 23, 2012
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Repeat EK an effective treatment option after failed DSEK

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Repeat endothelial keratoplasty was a successful treatment option after failed Descemet’s stripping endothelial keratoplasty, a study found.

 “Repeat EK in patients with DSEK failure is an effective treatment modality. This is the preferred management option compared with penetrating keratoplasty because the advantages of EK surgery … such as rapid visual recovery, minimal refractive change and structural integrity, are preserved with repeat EK surgery,” the study authors said.

The retrospective cohort study included 20 eyes of 20 patients who underwent repeat endothelial keratoplasty (EK) after failed DSEK. The failed DSEK donor disk was removed from all eyes.

The mean age at initial surgery was 69.9 years. The mean time from initial surgery to repeat EK was 13.1 months. Mean follow-up was 27 ± 13.4 months.

No intraoperative complications were noted, and no episodes of rejection or graft failure after repeat surgery were seen at final follow-up.

Mean logMAR corrected distance visual acuity improved from 1.76 preop to 0.5 at final follow-up (P < .001).