October 09, 2012
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Corneal power may increase up to 7 years after LASIK

Corneal stability was achieved 1 year after PRK, while instability remained 7 years after LASIK, according to a study.

In the prospective study, 45 patients with myopia of –6 D to –8 D were randomized to receive either PRK or LASIK. PRK was performed in 20 patients, and LASIK was performed in 25 patients. Follow-up continued up to 7 years postoperatively.

At 3 years postop, 16 PRK patients and 15 LASIK patients were available for examination. At 7 years postop, nine PRK patients and seven LASIK patients were available for examination.

In LASIK patients, corneal power increased from 44.39 ± 1.80 D at 1 month postop to 45.01 ± 1.87 D at 1 year postop (P < .01). Corneal power also increased from 1 to 3 years postop (P < .05) and from 3 to 7 years postop (P < .05).

In PRK patients, corneal power increased from 44.26 ± 1.82 D at 1 month postop to 45.39 ± 2.16 D at 1 year postop (P < .001). No significant changes were observed past the 1-year follow-up.

Spherical aberrations were significantly higher at all follow-up points after LASIK than prior to surgery (P < .01).

With PRK, spherical aberrations increased significantly at 1 month postop (P < .001). At all follow-up points between 3 months and 7 years, spherical aberration remained stable and significantly higher than before PRK (P < .01).

“Although newer lasers and treatment algorithms may show higher refractive predictability and less induction of higher-order aberrations, the results suggest that surgically induced higher-order aberrations do not readily diminish over time,” the study authors said.