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Spherical equivalent, IOP associated with ocular pulse amplitude
Ocular pulse amplitude in glaucoma suspects and patients with open-angle glaucoma is associated with IOP and spherical equivalent, according to a study.
The prospective study enrolled 173 glaucoma suspects, of which 74 were diagnosed with open-angle glaucoma. IOP was measured by dynamic contour tonometry and Goldmann applanation tonometry. Patients also underwent Humphrey visual field examination and central corneal thickness measurements.
Ocular pulse amplitude was associated with spherical equivalent in all 173 eyes (P < .001), as well as with IOP measured by Goldmann applanation tonometry (P = .013).
For 77 eyes, patients’ blood pressure parameters were available. Of those eyes, ocular pulse amplitude was associated with spherical equivalent (P = .007) and IOP measured by Goldmann applanation tonometry (P < .001).
There was no difference in ocular pulse amplitude when patients were classified according to low, intermediate or high cardiovascular risk.
“Thus, [ocular pulse amplitude] is primarily a measure of pressure, and there are certain limitations towards its use as a hemodynamic index,” the study authors said.