August 23, 2012
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Vitrectomy yields similar outcomes with temporary keratoprosthesis or endoscopy

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Vitrectomy yielded comparable visual and anatomic outcomes whether performed with temporary keratoprosthesis or endoscopy in eyes with opaque cornea due to ocular trauma, a study found.

“Endoscopy allows earlier diagnosis and treatment of occult pathology and requires less time and fewer procedures to implement than the temporary keratoprosthesis,” the study authors noted.

The retrospective study included 17 eyes of 16 patients who underwent vitrectomy with temporary keratoprosthesis or endoscopy at a single center between 2003 and 2010. All eyes had from ocular trauma-associated opaque cornea allowing no visualization of the intraocular space and requiring vitrectomy.

Eight eyes of eight patients underwent vitrectomy with a 7-mm Eckardt temporary keratoprosthesis (Dutch Ophthalmic USA). Endoscopy was performed with an Endo Optiks E2 endoscopy system in nine eyes of eight patients.

Macular membrane stripping (P = .029) and perfluoro-n-octane (P < .0005) were performed significantly more frequently in the keratoprosthesis group. All eyes in the keratoprosthesis group received a corneal allograft after vitrectomy.

Study results showed that two eyes in the keratoprosthesis group and four eyes in the endoscopy group had best corrected visual acuity of at least 20/200 at 3 months. At 6 months, one eye in the keratoprosthesis group and four eyes in the endoscopy group had BCVA of 20/200 or better.

Overall, 10 eyes (59%) had retinal detachment at baseline and three eyes (18%) had retinal detachment at 6 months.

No surgical complications were reported, the authors said.